Guideline Central Blog

Monographs

Fluticasone Furoate, Umeclidinium, & Vilanterol Inhalation Powder (Trelegy Ellipta/GSK) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication fluticasone furoate, umeclidinium, and vilanterol, marketed under the brand name Trelegy Ellipta by GlaxoSmithKline. Trelegy Ellipta is a combination of fluticasone furoate, an inhaled corticosteroid (ICS); umeclidinium, an anticholinergic; and vilanterol, a long-acting beta2-adrenergic agonist (LABA) indicated […]

Aflibercept (Eylea/Regeneron) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication aflibercept, marketed under the brand name Eylea by Regeneron Pharmaceuticals, Inc. Eylea a is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration (AMD), Macular Edema […]

Vedolizumab (Entyvio/Takeda) – Guidelines+ Monographs

Welcome to the latest installment of our Guidelines+ Monographs Series. In this edition, we will delve into the medication vedolizumab, marketed under the brand name Entyvio by Takeda Pharmaceuticals. Entyvio is an integrin receptor antagonist indicated in adults for the treatment of moderately to severely active ulcerative colitis (UC) and moderately to severely active Crohn’s […]

Aripiprazole (Abilify Asimtufii/Otsuka) – Guidelines+ Monographs

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication aripiprazole, marketed under the brand name Abilify Asimtufii by Otsuka Pharmaceutical Co., Ltd. Abilify Asimtufii (aripiprazole) is a long-acting injectable atypical antipsychotic for the treatment of schizophrenia and bipolar I disorder. It was initially approved in […]

Naltrexone (Vivitrol/Alkermes) – Guidelines+ Monographs

Welcome to the newest installment of our Guidelines+ Monographs Series. Today, we will be exploring the medication naltrexone, specifically the injectable form marketed under the brand name Vivitrol by Alkermes, Inc. Vivitrol is an opioid antagonist that was first approved in 2006. It is prescribed for the treatment of alcohol dependence and to block the […]

Brexpiprazole (Rexulti/Otsuka/Lundbeck) – Guidelines+ Monographs (August 2024 Edition)

Welcome to the latest edition of our Guidelines+ Monographs Series. In this installment, we will delve into the medication brexpiprazole, marketed under the brand name Rexulti by Otsuka America Pharmaceutical, Inc and Lundbeck LLC. Rexulti, an atypical antipsychotic, received initial approval in 2015. It is indicated for  use as an adjunctive therapy to antidepressants for […]

Olaparib (LYNPARZA) – Guidelines+ Monographs

In this installment of our Guidelines+ Monographs Series, we will delve into the medication olaparib, marketed under the brand name Lynparza by AstraZeneca. Lynparza, is a poly ADP ribose polymerase (PARP) inhibitor for the treatment of ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. It was initially approved in 2014. In the following sections, […]

Niraparib (ZEJULA/GSK) – Guidelines+ Monographs

Ovarian cancer, the 5th leading cause of cancer deaths in the U.S., is one of the deadliest gynecologic malignancies due to its mild early symptoms, often leading to late detection. This edition of our Guidelines+ Monograph series explores niraparib (brand name Zejula) from GlaxoSmithKline (GSK), a once-daily oral (PO) PARP inhibitor. It’s FDA-approved as a […]

Naloxone Hydrochloride (NARCAN/Emergent) – Guidelines+ Monographs

The opioid crisis continues to be a major public health issue, with overdose rates still rising in many areas, particularly due to the increasing prevalence of synthetic opioids like fentanyl. This edition of our Guidelines+ Monograph series will be dedicated to International Overdose Awareness Day, a day on August 31st of each year dedicated to […]

Dapagliflozin (Farxiga/AZ) – Guidelines+ Monographs (August 2024 Edition)

In this edition of our Guidelines Monographs Series, we will be taking a look at AstraZeneca’s medication dapagliflozin, brand name Farxiga. Initially approved in 2014, Farxiga is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, provided to individuals with diabetes, heart disease, or kidney disease to improve their outcomes. This Guidelines+ Monograph will take a deeper dive […]

Apixaban (Eliquis) – Guidelines+ Monographs (July 2024 Edition)

In this edition of our Guidelines+ Monographs Series, we will be taking a look at Bristol-Myers Squibb’s medication apixaban, brand name Eliquis. Initially approved in 2012, Eliquis is a factor Xa inhibitor, an anticoagulant used to prevent stroke and systemic embolism in nonvalvular atrial fibrillation, and to treat deep vein thrombosis (DVT) and pulmonary embolism […]